This study investigates how the effects of MDMA evolve over time when used in therapeutic contexts. Specifically, it examines how repeated MDMA-assisted sessions influence emotional intensity, the development of tolerance, and therapeutic outcomes over months and years. The research draws on a combination of retrospective and prospective data, including documented session notes spanning over 9 years, participant interviews, and optional surveys.
By focusing on real-world therapeutic use—including informal settings—this study aims to explore whether reduced emotional intensity over time necessarily diminishes therapeutic value, or whether long-term transformation can occur even as the initial “magic” of MDMA fades. A central question is whether spacing between sessions affects the re-emergence of strong emotional responses, and how this interacts with perceived therapeutic progress.
The mixed-method, longitudinal approach allows for deep insight into both the experiential and functional dimensions of MDMA’s long-term impact. The study also seeks to contrast these findings—where possible—with data or outcomes from formal clinical settings, in order to contextualize the sustainability and effectiveness of MDMA-assisted therapy beyond the boundaries of short-term clinical trials.
STATUS: In pre-implementation phase; undergoing ethics committee review.